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Treatments

Over-the-counter fungal nail treatments compared

2 min read Reviewed

Pharmacy shelves offer three quite different mechanisms, and they suit different stages of infection. Matching the product to the nail matters more than the brand on the box.

Summary

Medicated lacquers are for mild infection of the nail tip. Nail-removal sets using 40% urea are for thicker, more established infection where a lacquer cannot penetrate. Antifungal solutions and creams are mainly for the surrounding skin.

The main options

What each is designed to do.

  • Amorolfine 5% lacquer — weekly application, 6–12 months, mild distal infection
  • 40% urea ointment set — daily under a plaster for 2–4 weeks to remove diseased nail
  • Tioconazole 28% solution — twice daily to nail and folds, up to 12 months
  • Antifungal cream — for athlete's foot on the surrounding skin

Choosing

If more than half the nail is affected, if the nail is visibly thickened, or if the infection reaches the cuticle, a lacquer alone is unlikely to succeed. Removing the diseased nail first is what gives any subsequent treatment a chance.

When to seek medical advice

Ask a pharmacist if you are pregnant, breastfeeding, diabetic, treating a child, or already taking regular medication.

Frequently asked questions

Can I use a lacquer and a removal set together?

Many people remove the diseased nail first, then use a topical antifungal on the exposed bed. Ask your pharmacist about the specific products.

Which is fastest?

Nail removal deals with the infected material in weeks; lacquers rely on months of nail growth.

References

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Medical disclaimer. This article is general information written for a UK audience. It is not medical advice and does not replace assessment by a GP, pharmacist or podiatrist. Always read the patient information leaflet supplied with any product before use.